Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming
نویسندگان
چکیده
منابع مشابه
I-19: Identifying and Overcoming an Epigenetic Barrier for SCNT Reprogramming
Background Despite successful cloning of many mammalian species, the cloning efficiency is extremely low compared to that of IVF raising the possibility of the existence of epigenetic barrier preventing successful cloning. MaterialsAndMethods Using comparative transcriptome analysis comparing transcriptomes of IVF and SCNT embryos and that of donor cells, we identified epigenetic barrier and fi...
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ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2016
ISSN: 1934-5909
DOI: 10.1016/j.stem.2016.02.003